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Population Genetics
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== <span style="color: #FFFFFF;">Applying</span> == '''Modeling 'The Hardy-Weinberg Equilibrium' (Predicting carrier rates):''' <syntaxhighlight lang="python"> def calculate_carriers(disease_frequency): """ If q^2 is the rate of people with a disease, what is 2pq (the rate of healthy carriers)? """ import math # q is the sqrt of the disease rate q = math.sqrt(disease_frequency) p = 1 - q carriers = 2 * p * q return { "Disease (q^2)": f"{disease_frequency*100:.2f}%", "Carrier (2pq)": f"{carriers*100:.2f}%", "Healthy (p^2)": f"{p**2*100:.2f}%" } # Cystic Fibrosis affects ~1 in 2,500 people in some groups print(calculate_carriers(1/2500)) # Even though the disease is rare, the math shows that # about 1 in 25 people are healthy carriers! </syntaxhighlight> ; Genetic Landmarks : '''The 'Modern Synthesis' (1930s)''' β The great unification where math, genetics, and Darwin's evolution were merged into a single science. : '''Out of Africa Theory''' β Using population genetics to prove that all modern humans share a common ancestry in Africa ~200,000 years ago. : '''Antibiotic Resistance''' β A real-time demonstration of "Natural Selection" where the 0.01% of bacteria that survive a drug quickly become 100% of the next generation. : '''Mitochondrial Eve''' β The mathematical "Mother" of all living humans, found by tracking the DNA passed only through mothers. </div> <div style="background-color: #8B4500; color: #FFFFFF; padding: 20px; border-radius: 8px; margin-bottom: 15px;">
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