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Antibiotic Mechanisms and Resistance
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== <span style="color: #FFFFFF;">Applying</span> == '''Modeling 'The Resistance Race' (Simulating how a population of bacteria survives a drug):''' <syntaxhighlight lang="python"> def simulate_resistance(population_size, drug_kill_rate, mutation_chance): """ Shows how 'One survivor' can restart the infection. """ survivors = population_size * (1 - drug_kill_rate) # Some survivors might 'Mutate' to be 100% resistant mutants = round(survivors * mutation_chance) if mutants > 0: return f"STATUS: FAILURE. {mutants} Superbugs survived. The infection will return." elif survivors > 0: return f"STATUS: SUCCESS (Partial). {round(survivors)} bacteria left. Immune system must finish." else: return "STATUS: CURED. All bacteria destroyed." # Case: Standard dose (99.9% kill). Population: 1 Million. Mutation chance: 0.001% print(simulate_resistance(1000000, 0.999, 0.00001)) # Case: Low dose/Missed days (80% kill). print(simulate_resistance(1000000, 0.80, 0.00001)) </syntaxhighlight> ; Antibiotic Landmarks : '''Penicillin (1928/1941)''' β The "Yellow Magic" that saved the Allies in WWII and added 20 years to the average human lifespan. : '''The 'Discovery Void' (1987-Present)''' β The fact that "No new class" of antibiotics has been discovered since the late 1980s. We are "Running out of ammo." : '''MRSA''' β A common hospital superbug that is "Immune to almost everything," forcing doctors to use "Toxic, Old-fashioned" drugs as a last resort. : '''Phage Therapy''' β Using "Viruses that eat bacteria" (Bacteriophages) as a "Living Medicine" to kill superbugs that are immune to chemicals. </div> <div style="background-color: #8B4500; color: #FFFFFF; padding: 20px; border-radius: 8px; margin-bottom: 15px;">
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