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DNA Replication and Repair
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== <span style="color: #FFFFFF;">Remembering</span> == * '''DNA Replication''' β The process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. * '''DNA Polymerase''' β The "Builder" enzyme that adds new nucleotides to the growing DNA strand. * '''Helicase''' β The "Unzipper" enzyme that breaks the hydrogen bonds between DNA bases to open the double helix. * '''Primase''' β The "Initializer" enzyme that places a small RNA primer to show polymerase where to start. * '''Ligase''' β The "Gluer" enzyme that seals the gaps between DNA fragments (Okazaki fragments). * '''Okazaki Fragments''' β Short sequences of DNA nucleotides synthesized discontinuously on the "lagging" strand. * '''Mutation''' β A change in the DNA sequence that can occur during replication or due to environmental damage. * '''Mismatch Repair (MMR)''' β A system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases. * '''Nucleotide Excision Repair (NER)''' β A mechanism that removes DNA damage induced by UV light (like a "Cut and Paste" repair). * '''Double-Strand Break (DSB)''' β A severe type of DNA damage where both strands of the helix are broken; repaired by NHEJ or Homologous Recombination. </div> <div style="background-color: #006400; color: #FFFFFF; padding: 20px; border-radius: 8px; margin-bottom: 15px;">
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