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AI for Personalized Medicine
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== <span style="color: #FFFFFF;">Remembering</span> == * '''Precision medicine''' β Medical care tailored to the individual based on their unique genetic, molecular, and lifestyle profile. * '''Biomarker''' β A measurable biological indicator (genetic variant, protein level, imaging feature) predicting disease risk, diagnosis, or treatment response. * '''Pharmacogenomics''' β How genetic variation affects drug metabolism and response; the foundation of drug personalization. * '''Companion diagnostic''' β An FDA-approved diagnostic test paired with a specific drug to identify patients who will benefit. * '''Tumor mutational burden (TMB)''' β A biomarker predicting immunotherapy response across cancer types. * '''HLA typing''' β Identifying human leukocyte antigen variants that predict drug hypersensitivity reactions and transplant compatibility. * '''Multi-omics''' β Integrating genomics, transcriptomics, proteomics, metabolomics, and microbiomics for comprehensive patient profiling. * '''Patient stratification''' β Dividing patients into subgroups with different predicted responses to guide treatment decisions. * '''Predictive biomarker''' β Predicts response to a specific treatment (vs. prognostic biomarker, which predicts disease outcome regardless of treatment). * '''Liquid biopsy''' β Blood test detecting circulating tumor DNA or cells; enables non-invasive personalized tumor monitoring. * '''Digital twin (personalized medicine)''' β A computational model of an individual patient for simulating treatment responses. * '''N-of-1 trial''' β A clinical trial with a single patient cycling through treatments to determine individual optimal therapy. * '''Polygenic risk score (PRS)''' β ML-derived score from thousands of genetic variants predicting individual disease risk. * '''Wearable integration''' β Using continuous physiological data from wearables to personalize treatment and monitoring. </div> <div style="background-color: #006400; color: #FFFFFF; padding: 20px; border-radius: 8px; margin-bottom: 15px;">
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